The town is known for its medieval buildings and the fact that Isabella I of Castile spent her childhood there.

The museum is located in the ancient Sexmos´s House and is run by the Arévalo town hall.

The Arévalo History Museum houses approximately one hundred pieces.

The museum also has several recreations of the town's main historic buildings.

The museum also has a hall dedicated to the heritage of Autun, France, which is the sister city of Arévalo and has been since 2005.