Museo Nazionale Scienza e Tecnologia Leonardo da Vinci in Milan, dedicated to painter and scientist Leonardo da Vinci, is the largest science and technology museum in Italy.

It was opened on 15 February 1953 and inaugurated by Prime Minister Alcide De Gasperi.

The Transport section is made up of four different parts: air, rail, water and Submarine Enrico Toti-S-506.

Specific sections are dedicated to polymeric and synthetic materials and to basic chemical manufacturing.

In this part of the museum there is the Margherita thermoelectric power station (1895) and an oil industry/petrochemistry section.