The Museu Barbier-Mueller d'Art Precolombí (its local name in Catalan; also known in Spanish: Museo Barbier-Mueller de Arte Precolombino, and in English: Barbier-Mueller Pre-Columbian Art Museum) was the only museum in Europe devoted exclusively to the artistic legacy of the pre-Columbian cultures of the Americas.

It was located in the Catalan capital of Barcelona, Spain.

In 2012, the museum was unable to reach a purchase agreement with the collection's owner Jean Paul Barbier-Mueller.

Subsequently, the world's most important Pre-Columbian collection in private hands (according to El País) was split and auctioned at Southeby's on 22 March 2013.

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