The collection includes paintings, sculptures, furniture and applied art, illustrating the cultural history of Dortmund from early times to the 20th century.
It changed location several times in the early years, and came to include archaeological finds, decorative artworks and local historical artefacts.
[7] The permanent collection of 19th-century paintings includes works by Caspar David Friedrich (Winter Landscape and The Temple of Juno in Agrigento), Max Slevogt, Lovis Corinth and Anton von Werner.
Some of the previous temporary exhibitions have been devoted to Ernst Ludwig Kirchner, Friedrich Karl Waechter, Paul Cézanne, Édouard Manet, and Frank Lloyd Wright and The Living City (2000).
[9] An exhibition from May 13 to October 14, 2018, examined the provenances of pictures acquired during the war years under the museum's director Rolf Fritz.