Music Note (born February 5, 2005, in Kentucky) is retired American Thoroughbred racehorse who was a five-time Grade I stakes winner.

At age three, she won the Gazelle, Mother Goose and Coaching Club American Oaks, then finished third to Zenyatta in the Breeders' Cup Ladies Classic.

Music Note is a bay mare who was bred in Kentucky by Gainsborough Farm, the American breeding arm of Godolphin Racing.

She was produced by the unraced mare Note Musicale, who was by leading Irish stallion Sadler's Wells and out of champion It's In the Air.

[4] On June 28, her connections stepped her sharply up in class by entering her in the Grade I Mother Goose Stakes, then considered the first leg of New York's Triple Tiara for fillies.

Entering the stretch, Music Note went to the lead while Proud Spell had to check her stride due to a lack of racing room on the rail and fell back to fourth.

[6] In the absence of Proud Spell, Music Note and her stablemate Little Belle were the odds-on favorites in the Coaching Club American Oaks on July 19.

Little Belle took the early lead with Proud Spell close behind and Music Note at the back of the tightly bunched field while racing four-wide.

Proud Spell took the lead entering the stretch and then held off a sustained drive from Music Note to win by a head.

"[2][9][10] Music Note became the overwhelming 1-20 favorite in the Gazelle Stakes on September 13 when her main rival Country Star was scratched after throwing her rider.

Music Note settled at the back of the main pack with Cocoa Beach, trailed only by the late-running Zenyatta.

The three horses still trailed the field after three-quarters of a mile but then started to move into contention, with Music Note five-wide around the final turn.

A relative longshot at 6-1, Music Note started at the back of the field then found room on the rail to take the lead on the turn.

[19] Music Note made her final start in the 2009 Breeders' Cup Ladies Classic on November 6, held at Santa Anita.