Brothers Josh and Mike are enjoying a vacation in the South when they are run off the road by Al and a few of his friends.

Al (who is a custodian) accuses him of murder and chases him off, leaving with Holly to her uncle's place where he recovers from the toxic reaction from the girl.

Will goes to the schoolgirl's residence, where he sees the lightbulbs removed and all the red meat sucked dry.

Next morning Josh and Holly head out to a plant that some chemical company just opened a few weeks ago, thinking that this could be the cause of the sickness.

Will is reluctant to believe their story, but when he sees Holly's uncle become a mutant, they formulate a plan to get the girls body and take it to the capital to get backup.

Suddenly, a large group of state police cars surround the gas station shining their lights.

During production, Mutant went through several title changes including Night Shadows and Toxic Waste as well as differing approaches to the material.

[2] Mark Rosman was originally hired to direct but was falling behind schedule due to his precise and methodical shooting approach that also removed flexibility during the editing process.

Special features include an on-camera interview with actors Bo Hopkins and Lee Montgomery, an audio commentary with Lee Montgomery, Igo Kantor and director John Bud Cardos, and the original theatrical trailer.

The film is also on the "200 Tales of Terror" DVD set released by Mill Creek Entertainment.

The score, performed by the National Philharmonic Orchestra, has been highly acclaimed over the years for its massive size, often lyrical scope and a surprisingly melodic nature.