The song performed greatest in the United States reaching a peak of number nine on the Billboard Hot 100 and has gone on to sell 1,800,000 copies in the country as of 2016.

"My First Kiss" was written by Sean Foreman and Nathaniel Motte alongside Dr. Luke and Benny Blanco.

The song was produced by Dr. Luke and Benny Blanco with vocal editing done by Emily Wright.

[5] According to Sara D Anderson of AOL Radio, Kesha plays the role of a boy's first crush "who decides to not let him go past first base: 'She don't wanna give it up / Baby I can get it up / If I had it my way / Hey!

Copsey commented that the song was simply "another shouty electro-hop nugget that's as rowdy and intimidating as the school bully after a can of Red Bull".

[4] Lamb wrote "[though] part of me wants to find this terribly annoying" that hardly matters as "3OH!3 and Kesha are probably the most gifted artists of the moment performing irresistibly catchy music".

"[4] In the United States, "My First Kiss" entered the US Billboard Hot 100 on the issue date titled May 22, 2010, at number nine where the single reached its peak.

[9] The song went on to sell over 500,000 copies in 2010 in the United States and has since been certified gold by the Recording Industry Association of America (RIAA).

[12] In October 2010 the single was certified platinum by the Canadian Recording Industry Association (CRIA) for sales of 80,000 units.

[14] The song was listed on the chart for a total of 17 weeks and has since received platinum certification by the Australian Recording Industry Association (ARIA) for sales of 70,000 units.

It features a lot of people (punks, teachers, sailors, soldiers, lesbians, nerds, an elderly couple and hirsute rockers) "smooching, kissing, and making out.

The main scenes present are of "3OH!3 bouncing around and throw[ing] punches at the camera"[17] while singing their versus and occasional close-ups of different pairs of lips that are mouthing different lyrics of the song.

Kesha is also present throughout the video, mainly on her verses where she is seen in close-ups of her lips and dancing around the screen on the chorus.