[1] The game centers on protagonist Junichiro Hondo who awakes one morning to discover his next-door-neighbor and lifelong friend Yukino Ohama has suddenly become president of the fictitious United States of Nippon (Japan).
[2] The player assumes the role of Junichiro Hondo, alike a typical visual novel, the amount of game play is minimal.
Occasionally interactions in the game are required to progress to the proceeding scene, by selecting one of the options/choices that appear in the center of the screen.
To avoid chaos, the extraterrestrials brainwash the populace into the belief that Junichiro's childhood friend Yukino Ohama is leader of the country of Nippon.
[2] The majority of the game's events and scenarios occur in the United States of Nippon, which is being controlled by Yukino, who was brainwashed to believe she is the president.
[3] Yukino Ohama, arguably the most iconic character, is Junichirō's neighbor and childhood friend who was selected to be president of Nippon after the accidental destruction of the previous administration.
Since she set forth the "Jun-kun Supremacy Doctrine" and has a troublesome side of passing crazy laws for the sake of love, disputes between Junichiro and the bureaucrats never die out.
[3] Irina Vladimirovna Putina is an active duty president who reigns over "Rusia" (Russia) with super charisma.
She obtains information that a UFO crashed into Nippon, and visits to talk about laws dealing with import restrictions.
On the day of her visit, Irina is seen assaulting a strange man and when she strikes back, Junichiro rescues her, which causes her to become dumbstruck.
As it turns out, the man placed a bomb in the building because he suspected something similar to this may happen, so Junichiro escapes with Irina heroically and afterwards she exposes her gratitude.
She later visits the Snow House as a guest of Yukino and is able to recognize James Hondo (Junichiro gave her a fake name when they first met), she hugs him to everyone's shock and tells him to become her husband.
She fosters a rivalry against the childhood friend president who's also the head of the student council, and seems to have plans to correct the entire school as a disciplinarian.
[3] Starship Ezekiel (called "Ell") is a state-of-the-art UFO designed to take the appearance and actions of a young girl whilst upholding the task of protecting the other characters.
As a mysterious woman with an obscure private life, she also works part-time at a Chinese restaurant while serving as Yukino's Chief of Staff.
He often walks around without a shirt on for an unknown reason, Morita is actually a space detective who administrates a secret agency named Coalition Headquarters.
Starship Jeremiah, better known as Remi, is the older sister of Ell, despite her noticeably short stature and bust size.
Alcot officially released the company's ninth game Osananajimi wa Daitouryou: My girlfriend is the President - Trial Edition on 18 September 2009, with an age rating of 17+.
Then the first press limited edition game was officially published and released on 30 October 2009, the age rating was raised to 18+.
Due to the popularity of the eroge, a fan disc of Osananajimi wa Daitouryou: My girlfriend is the President published by Alcot, was officially released in Japan on 13 August 2010.
My Girlfriend is the President's fan disc opening theme is Dramatic Parade sung by Aya Tachibana.