My Sister Eileen is a 1942 American comedy film directed by Alexander Hall and starring Rosalind Russell, Brian Aherne and Janet Blair.

Fields and Jerome Chodorov is based on their 1940 play of the same title, which was inspired by a series of autobiographical short stories by Ruth McKenney originally published in The New Yorker.

Ruth Sherwood, a reporter for the Columbus Courier, finds herself embroiled in a series of misfortunes after inadvertently publishing a premature and erroneous review of her sister Eileen's theatrical performance.

Encouraged by their grandmother, the two sisters, Ruth and Eileen, decide to relocate to New York City, armed with meager financial resources provided by their father.

As Ruth and Eileen navigate the complexities of city life, they find themselves embroiled in a whirlwind of events, including romantic entanglements, professional aspirations, and familial discord.

But Rosalind Russell plays the smart sister with a delightfully dour and cynical air, and Janet Blair is disarmingly naive as the pretty, desirable one .