Myoporum oppositifolium is an erect shrub which grows to a height of 1–2 metres (3–7 ft) and has glabrous branches which usually have raised, wart-like tubercles.

Flowering occurs throughout the whole year and is followed by lilac to brown fruits which are drupes, 2.5–5 millimetres (0.1–0.2 in) in diameter and roughly spherical in shape.

[2][3] Myoporum oppositifolium was first formally described in 1810 by Robert Brown and the description was published in Prodromus Florae Novae Hollandiae.

[5] Twin-leaf myoporum occurs along the coast of Western Australia from near Busselton to near Albany in the Esperance Plains, Jarrah Forest and Warren biogeographic regions.

[2][6] Myoporum oppositifolium is classified as "not threatened" by the Western Australian Government Department of Parks and Wildlife.