In 2013, in a redistricting case heard by a three-judge panel, Thompson disagreed with its decision contending it was an illegal use of racial quotas.

He wrote that Alabama's use of the Voting Rights Act was a "cruel irony," that as the state was simultaneously arguing before the Supreme Court in Shelby County v. Holder, that Section 5 should be found unconstitutional, it was "relying on racial quotas…and seeking to justify those quotas with the very provision it was helping to render inert.

"[2] On October 29, 2019, Judge Thompson issued a preliminary injunction blocking the Human Life Protection Act from taking effect in Alabama as prescribed on November 15, 2019.

Judge Thompson concluded, "The court is persuaded that the plaintiffs are likely to succeed in showing that the Act violates an individual’s constitutional right to obtain a pre-viability abortion, and thus that it violates her constitutional rights.

"[3] In 2014, in Planned Parenthood Southeast, Inc., v. Strange, (also known as Planned Parenthood Southeast, Inc., v. Bentley), Thompson ruled an Alabama law regulating abortion unconstitutional, citing the undue burden standard.