After struggling with numerous medical ailments for which orthodox medicine (of the day) fell short, she eventually "awoke" to spiritual self-healing which she credited for greatly improving health, including recovery from chronic tuberculosis.

The family then moved to Omaha, Nebraska and then Kansas City, Missouri, where their third son, Royal, was born in 1889.

Myrtle subsequently recovered from chronic tuberculosis and attributed her recovery to her use of prayer and other methods learned in Weeks' classes.

Subsequently, Charles began to heal from his childhood accident, a development which he too attributed to following this philosophy.

Although Charles had no intention of making Unity into a denomination, his students wanted a more organized group.

Charles and Myrtle Fillmore operated the Unity organizations from a campus near downtown Kansas City.