The entry doors are surrounded with a transom and sidelights, showcasing original hand-painted stained glass, etched and patterned after the French cross to allegedly ward off evil.

The main feature of the Myrtles is the 125-foot-long veranda that extends the entire length of the façade, and wraps around the southern end of the house.

The west facing rear façade features a central, open loggia that is enclosed on three sides by the house, and on the roof are five pedimented dormers identical to the front.

The spacious entry hall runs the length of the house and features faux-bois, open pierced friezework molding, a French Baccarat crystal chandelier weighing more than 300 pounds and a cantilevered staircase.

The two parlors feature Carrara marble mantles in the Rococo Revival-style on the north and south walls, and are crowned with elaborate plaster cornices and ceiling medallions, made from a mixture of clay, Spanish moss and cattle hair, with no two being the same.

The largest bedroom, known as the Judge Clarke Woodruff Suite, is the only room that is accessed by the main staircase in the entry hall.

The Myrtles Plantation was built in 1796 by General David Bradford on 600 acres (0.94 sq mi; 2.4 km2) in what was then part of Spanish West Florida and was named "Laurel Grove."

Bradford lived there alone for several years, until President John Adams pardoned him for his role in the Pennsylvania Whiskey Rebellion in 1799.

[6][7] When Elizabeth Bradford died in 1831, Clarke Woodruff and his surviving daughter Mary Octavia moved to Covington, Louisiana, and left a caretaker to manage the plantation.

The family fortune was lost in the aftermath of the war due to it being tied up in Confederate currency, and the Winters were forced to sell the plantation in 1868, but were able to buy it back two years later.

In August 2014, a fire occurred in the historical General's Store, located just 10 feet from the main house, causing substantial damage.

[4] Listed on the National Register of Historic Places, the Myrtles Plantation continues to be a popular tourist attraction due to its association with paranormal activity, and has been featured in many books, magazines, newspapers and television shows.

[citation needed] The plantation was featured on the second episode in the first season of the television series Files of the Unexplained, airing in April 2024.