Mystery Diagnosis is a television docudrama series that aired on Discovery Health Channel and OWN: Oprah Winfrey Network.
Each episode focuses on two or more individuals who have struggled with obscure medical ailments, and their quest for a diagnosis.
After continuing to experience symptoms for an extended period of time, the person discovers a doctor who is able to solve their case.
The doctor reviews the patient's medical records, notices a symptom that his or her colleagues overlooked, performing tests, and finally reaching the correct diagnosis and giving the proper treatment.
A significant number of episodes revolve around autoimmune disorders, ranging from Pyoderma gangrenosum to Paraneoplastic cerebellar degeneration.