The league is one of the leading competitions for female footballers to be recruited to AFL Women's (AFLW) clubs.
An identical competition for male footballers, known as the Talent League Boys, is also contested on an annual basis.
All NAB League Boys clubs entered teams and shared training grounds.
Carlton vice-captain Madeline Keryk said the competition helped equalise opportunities for boys and girls in junior football.
The Calder Cannons won all five of their matches and overcame the Murray Bushrangers on percentage to claim the inaugural premiership.