De La Salle-College of Saint Benilde is the host of the 2006–07 season, with this year's theme “Proud and True at 82: Blazing Beyond Limits.” NBI agents were present in the Ninoy Aquino Stadium, monitoring the basketball games.

The suspects "resurfaced" during the first round game between the Blazers and the Heavy Bombers, the day where the agents were supposedly absent.

[1] Samuel Ekwe got four out of five awards given by the NCAA Press Corps:[2] Elvin Jake Pascual won the MVP award in the Juniors' division,[2] He made history as the first Juniors player to sweep MVP, Rookie of the Year, Mythical Five, and Most Defensive Player awards in a single season The NCAA Cheerdance Competition was held on September 8, 2006 at the Araneta Coliseum.

The UPHSD PerpSquad successfully defended their championship, while the Letran Cheering Squad and the Mapúa Cheerping Cardinals all improved their places as compared from last year.

ABS-CBN Corporation subsidiaries Studio 23 and The Filipino Channel broadcast the Playoffs series and selected elimination round games.