It was hosted by the Mapúa Institute of Technology, now Mapúa University and was opened on June 27, 2015, at the Mall of Asia Arena in Pasay hosted by Andrei Felix and Myrtle Sarrosa and ended on March 8, 2016, with the Cheerleading Competition and closing ceremonies held at the MOA Arena, which was also hosted by Felix and Sarrosa, together with Anton Roxas, Migs Bustos, Ceej Tantengco and Roxanne Montealegre.

This was the first season after the NCAA renewed broadcasting deal with ABS-CBN Sports, after a 3-year contract with Sports5.

[1] Lyceum of the Philippines University and Emilio Aguinaldo College were accredited as full members of the NCAA, based from their performance in Season 90.

[2] In the end of the season, San Beda College regain the general championship title, dethroning De La Salle-College of Saint Benilde in seniors, and also having a 3-peat championship for the juniors division.

Basketball tournaments were officially opened on June 27, 2015, at the Mall of Asia Arena.

*Game went into overtime The volleyball tournament started on November 30, 2015, at the Filoil Flying V Arena.

The NCAA Season 91 beach volleyball tournament will be held on February 10–14, 2016 at the Marina Bay Resort, Subic, Zambales.

The football tournament will be start on December 1, 2015, at the Rizal Memorial Coliseum.

The San Beda College men's swimming team extended its domination of the NCAA to a 14th straight year, while its women's team completed a four-peat in the Season 91 swimming event that concluded over the weekend at the Rizal Memorial Swimming Center.

The NCAA Season 91 Cheerleading Competition will be held at the SM Mall of Asia Arena in Pasay on March 8, 2016.

The network will air Men's Basketball, Women's Volleyball (Final Four and Finals) tournaments, and NCAA Cheerleading Competition via ABS-CBN Sports and Action, Balls HD 167 (basketball tournament only), ABS-CBN Sports and Action HD 166 (volleyball tournament) ABS-CBN Sports and Action (international), and sports.abs-cbn.com every Monday, Tuesday, Thursday and Friday afternoons.