NGC 4298 is a flocculent[3][4][5][6] spiral galaxy located about 53 million light-years away[7] in the constellation Coma Berenices.

The galaxy was discovered by astronomer William Herschel on April 8, 1784[8] and is a member of the Virgo Cluster.

[13][2][14][16][15][17][18][4] Evidence for an interaction between the two galaxies are that NGC 4298 exhibits a lopsided, asymmetrical distribution of stars,[4][16][15] a tidal bridge that connects it to NGC 4302,[18][17][2] a prodigious rate of star formation[19] and an HI-tail.

[3] The two galaxies are separated from a projected distance of ~36,000 ly (11 kpc).

[20][15][3] The presence of a truncated gas disc,[3][4] an asymmetric 6 cm polarized radio continuum distribution,[13] an HI-tail,[3] and asymmetries of gas in a similar direction as the ram pressure stripped gas in NGC 4302 suggest that NGC 4298 is undergoing ram pressure.