NGC 4299 is a featureless spiral galaxy[2] located about 55 million light-years away[3][4] in the constellation Virgo.

[11][12] At the center of NGC 4299 lies a nuclear star cluster[13][14] with a diameter of ~5.9 ly (1.8 pc).

[12] As a result of a tidal interaction with NGC 4294, NGC 4299 has a disturbed optical and HI morphology,[16][11] with asymmetric spiral arms, a small, weak bar[10] and a high global star formation rate that appears to have been enhanced by ram-pressure.

[12] Chung et al. identified that NGC 4299 has a one sided[17][18] tail of neutral atomic hydrogen (HI).

[10][19] The tail points to the southwest[17][8] and appears to be a result of ram-pressure[19][20][10] or by a tidal interaction with NGC 4294.