It can be viewed through a moderately sized telescope with 23x magnification, forming a pair with an 11th magnitude star 1.5 arcminutes southwest.

The fact that they are the same object was noted by John Louis Emil Dreyer in 1912 in the corrections of the New General Catalogue.

[6] NGC 4665 has a luminous, slightly elliptical bulge and a prominent bar with high surface brightness.

An arch feature is observed at the east side of the galaxy that could be a partial outer dusty ring.

[15] These galaxies, along with NGC 4753, Messier 61 and their groups form the southern boundary of the Virgo cluster.