[1] The hospital was constructed inside the Manchester Central Convention Complex[2] and opened on 13 April 2020.

[3] As of 4 May, a small number of patients had been treated at the hospital.

Despite patient numbers remaining far below capacity, the hospital was not placed on standby like other Nightingale temporary hospitals in England, instead serving as a step-down facility for rehabilitation rather than an intensive care unit for patients requiring mechanical ventilation.

[5] By late June, the hospital had been placed on standby and was reported to have treated just over 100 patients in total.

[6] On 28 October 2020 amidst a rise in cases in Northern England, the hospital was reopened with 750 beds for patients from the region's hospitals without Coronavirus to free-up beds in those hospitals.