Her talent demanded that the family move to St. Petersburg for study at the conservatory, where the director, famed composer Alexander Glazunov, took a special interest in the gifted girl.

[2][4] Due to the upheavals of the October Revolution, Reisenberg and her family returned to Vilnius, then traveled to Warsaw and Germany.

[4] She then pursued further studies with Josef Hofmann at the Curtis Institute in Philadelphia, from which she graduated with a degree in piano performance.

[2][7] Reisenberg gave concerts in the 1920s, particularly with her sister Clara Rockmore, but in 1930 went to study again and chose Josef Hofmann as a tutor.

She was especially praised for her series of concerts encompassing all the piano concertos by Mozart, played (with Alfred Wallenstein conducting) for WOR, which was broadcast in the 1939/40 season.