Naftule Brandwein, or Naftuli Brandwine, (Yiddish: נפתלי בראַנדװײַן, 1884–1963) was an Austrian-born Jewish American Klezmer musician, clarinetist, bandleader and recording artist active from the 1910s to the 1940s.

[10] Brandwein emigrated to the United States in April 1909 (although some sources say 1908), sailing from Hamburg to New York City.

[11][10] He applied for US citizenship in 1912, adopting the Anglicized name Nathan Brandwein, although in his music career he continued to be known as Naftule.

[15][1] He stayed there for several years, making roughly two dozen recordings from 1923 to 1927, consisting mostly of virtuosic klezmer music put out under the label Naftule Brandwein Orchestra.

[18][19] His career declined from the mid-1920s onward, as demand for his traditional approach to klezmer music waned; his run of Victor Records sessions ended in 1927.

Among the klezmer revivalists who have been strongly influenced by him are David Krakauer, Hankus Netsky, Alicia Svigals, and Michael Winograd.