Nanbu Toshihisa (南部利剛, 25 January 1827 to 30 October 1896) was a Bakumatsu period Japanese samurai, and the 14th daimyō of Morioka Domain in northern Japan.

When Toshitomo was forced aside to permit the appointment of the more pliable Toshihisa, the domain erupted into widespread revolt in 1853.

The rōjū Abe Masahiro responding by placing both Toshitada and Toshitomo under house arrest in Edo, thus removing their influence over the government of the domain.

On 7 December, he was ordered to retire and was replaced as daimyō by his son, Nanbu Toshiyuki ten days later.

His eldest daughter married Prince Kachō Hirotsune, and one of his sons was adopted by Ōkuma Shigenobu.