Nancy Isime (born 17 December 1991) is a Nigerian actress, model, and media personality.

[1] Nancy Isime was born in Edo State to Nigerian parents of Esan descent.

[4][5] Nancy Isime began a career as an actress in the TV series Echoes in 2011.

[6] In 2016, she replaced Toke Makinwa as the presenter of the popular show Trending on HipTV.

[12] In 2022, she starred in the Netflix original series Blood Sisters, playing the lead role of Kemi, produced by Ebonylife TV studio which is owned by Mo Abudu.