These four systems enable scientists to envision molecular interactions in three dimensions and see the multiomic expression of genes and proteins in the context of tissue structure.

NanoString products are based on a novel digital molecular barcoding technology invented at the Institute for Systems Biology in Seattle under the direction of Dr. Leroy Hood.

[4] NanoString was spun out of The Institute for Systems Biology and founded as a separate company in 2003 by Krassen Dimitrov, Amber Ratcliffe, and Dwayne Dunaway.

The unique combination of high-plex and high-throughput spatial profiling allows researchers to rapidly and quantitatively assess the biological implications of heterogeneity within tissues and has resulted in over 150 peer-reviewed publications as of September 2022.

[11] The nCounter system allows for the simultaneous profiling of hundreds of genes, proteins, miRNAs, or copy number variations with high sensitivity and precision, using molecular barcodes and microscopic imaging in a hybridization reaction.

The GeoMx DSP combines whole tissue imaging with gene expression and protein data for single cell resolution in a spatial context.