[1] She has had guest spots voicing roles in the animated series Bob's Burgers, Family Guy, American Dad, Tuca & Bertie, and Central Park.

[5] After graduating from college, Ekperigin spent a year touring with the National Theatre for the Deaf,[5] and she returned to New York in 2007 where she got a start doing stand-up while working a day job at an art magazine.

[7] Splitsider praised her work as "savvy, smart, funny and politically active"[6] and Essence named her to its list of "8 Black Comediennes Who are 'Ready' for SNL.

Other projects include a pilot for TruTV called Inside Caucasia, developed with Ekperigin's partner, comedian Andy Beckerman.

[2] In June 2017, she joined the writing staff of the NBC sitcom Great News, starring Briga Heelan, Andrea Martin, and John Michael Higgins.