It was designed in the same Mediterranean Revival style the Seaboard Air Line used with its stations in Delray Beach, Deerfield Beach, Hialeah, and Homestead on the southeast coast of Florida (which were built around the same time), and is virtually identical to the Hialeah depot.

During World War II, the depot was also home to USO shows for troops stationed at the nearby Naples airfield.

The Atlantic Coast Line connected the former Seaboard track to their Fort Myers Southern Branch near Vanderbilt Beach, and resumed passenger service to the depot after an eleven-year absence.

Freight service was halted for good in the late 1970s, and the adjacent tracks were removed in 1980 (the remaining line from this point north is still in place and is now owned by Seminole Gulf Railway).

Displays include railroads, Seminole dugout canoes, a mule wagon and an antique swamp buggy.