She made her manga and character designer debut with Vampire Princess Miyu.
Kakinouchi made her key animation debut with her work on the 1980 series Space Runaway Ideon.
She then garnered great attention as the character designer, storyboard artist, and animation director for the Vampire Princess Miyu OVAs in 1988, and in March of that same year she co-authored the first Vampire Princess Miyu manga, serialized in the mystery/horror monthly manga magazine Susperia.
She made her directorial debut with Ryokunohara Labyrinth in 1990, in addition to being the character designer, scenario creator, storyboard artist, and animation director for the OVA.
[2] After a 16-year hiatus, in 2014 she returned to work as animator, serving as animation director of single episodes of The Pilot's Love Song, Date A Live II, Aldnoah.Zero, Psycho-Pass 2, Shirogane no Ishi Argevollen, Shinmai Maō no Testament, as well as TV episodes and a TV movie of Lupin the Third.