[14] After graduating from Jesus College, Oxford, Wei worked at McKinsey & Company for three years,[15] where he came to know Brett Wigdortz, who founded Teach First in 2002.

[16] In 2006, after three years at Teach First and a short stint in social venture capital, Wei joined the children's charity Absolute Return for Kids (ARK) where he helped to set up Future Leaders,[17] a programme seeking to attract, develop and place high-potential teachers and future leaders of urban schools.

Through the Shaftesbury Partnership, Wei co-founded The Challenge Network,[18] an independent charity which exists to "inspire and connect people to strengthen their community".

[22][23] Subsequently Lord Wei has also championed harnessing data science based approaches to help bring greater rigour and consistency to the process of policy development and impact venture incubation, through tools such as agent-based modeling,[24] AI-assisted swarm based prediction and decision-making tools,[25] and technology-aided impact measurement.

He and his team claim to offer strategy, impact and technological expertise[28] and he advises boards and founders on innovation and growth.

[36][37] The Prime Minister, David Cameron said 'Nat has worked incredibly hard over two years to help develop policies that support the Big Society.

He has played an important role in delivering key initiatives like Community Organisers, National Citizen Service, and the Big Society Bank.

"[38] Previously, Lord Wei had also cited personal financial difficulties that he had suffered as a result of the demands of his part-time position.

His ancestral home is two villages away from that of Sun Yat-sen, the founding father of the Republic of China, about whom incidentally, Wei enjoys reading and learning.

Up to July 2015, he worked in Parliament through the All Party Parliamentary Group APPG for East Asian Business which he chaired, the All Party Parliamentary China Group[41] of which he was the vice-Chair (special focus on Hong Kong), and the All Party Parliamentary Group for Trade and Investment[42] of which he was treasurer to promote better trade and political and cultural links between the UK and East Asia and work to encourage the next generation of East Asians and other diaspora to develop the leadership skills to play a greater role in public life, in society, and business, and in harnessing the resources that East Asians have globally and locally both financial and non-financial to address global and local problems today.

Following that Report,[43] a Manchester-China Forum[44] was established which hosts regular activities to help member businesses share information and knowledge, including seminars, meet-the-buyer events, and other networking opportunities.