[4] In 2013, Frank was diagnosed with a lack of stereoscopic vision—she has limited depth perception and needs corrective lenses, which the artist credits as the inspiration to create 3D figures.

[6][7] Frank's work is marked by disturbing, explicit, and grotesque subject matter that revolves around themes including women, sexuality, gender, violence, and humanity.

She often blurs the line between reality and fantasy, and the artist notes that she wants her work to be located on the edge of Magical Realism and the real world, the former in literature being a major source of inspiration for Frank.

[6] With oil on canvas and mixed media making up the bulk of her work, Frank is praised for her classical techniques that elicit references to the fleshy figures of Francis Bacon.

Titled "The Scene of Disappearance," the show included works depicting home life through intimate and grotesque portraits of bodies set in interior spaces, blurring the line between abstraction and realism.

The series marks the first time Frank drew inspiration from literature and is one of the only complex, systematic examination of the original tales by a contemporary artist.

Instead of working from life, Frank uses photographs of models that often include family and friends—a portrait of her father appears in "All Fur," and her grandfather's face floats next to the headless body of Bluebeard in one of the series' drawings.