Natalie Grandin (born 27 February 1981) is a retired tennis player from South Africa.

She achieved a career-high singles ranking of 144 as of 12 September 2005.

Grandin retired from professional tennis in January 2015.

Her father, Roy, is a project manager in IT while her mother, Rosamund, is a freight forwarder.

Grandin started playing tennis at age four.