Bertouch was a member of the Australia teams that won the gold medals at the 2007 and 2011 World Netball Championships.

At club level, Bertouch captained Adelaide Thunderbirds to two ANZ Championship titles in 2010 and 2013.

[9] Between 2004 and 2008, Bertouch attended Flinders University, where she gained a Bachelor's degree in Dietetics and Clinical Nutrition Services.

[8][16][17][18] In 2000, together with Tracey Neville, the Bertouch sisters were members of the Contax team that won the South Australia state league.

[16][24] In 2010, after finishing second during the regular season, they defeated the minor premiers, New South Wales Swifts, in the major semi-final and Waikato Bay of Plenty Magic in the grand final.

[25][26][27][28] In 2013, Natalie von Bertouch captained Thunderbirds to a second premiership after they defeated Queensland Firebirds in the grand final.

[24] Bertouch was a member of the Australia team that won the gold medal at the 2007 World Netball Championships.