Nataliia Lupu (born 4 November 1987) is a Ukrainian who specializes in 800 metres.

She finished fourth at the 2006 World Junior Championships.

[1] At the 2014 World Indoor Championships, she tested positive for the use of a prohibited stimulant, methylhexaneamine, receiving a 9-month ban.

The ban lasted from 7 March 2014 to 21 January 2015.

This biographical article relating to Ukrainian athletics is a stub.