Natalyino (Russian: Натальино) is a rural locality (a selo) in Natalyinsky Selsoviet of Blagoveshchensky District, Amur Oblast, Russia.

Natalyino is located on the right bank of the Zeya River, 91 km north of Blagoveshchensk (the district's administrative centre) by road.

Svetilovka is the nearest rural locality.

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