[2] In 2002, the NCRI exposed the existence of an undisclosed uranium enrichment facility in Natanz, leading to concerns about Iran's nuclear program.

In 2010, the International Atomic Energy Agency (IAEA) was told by the Iranian government that future enrichment programmes would take place at Natanz, and they would start in March 2011.

[12] Daily inspection by the IAEA of the Natanz site was agreed as part of the nuclear enrichment reduction agreement made with the P5+1 countries in November 2013.

[13] On 28 October 2020, the International Atomic Energy Agency (IAEA) released satellite images acknowledging that Iran had begun the construction of an underground plant near its nuclear facility at Natanz.

[15] Natanz's nuclear power plant was hit by a sophisticated cyber attack alleged to have been carried out in an operation called Olympic Games by a coalition of German, French, British, American, Dutch and Israeli intelligence organizations.

[17] The alleged goal of the cyber attack was not to destroy the nuclear program of Iran completely but to stall it enough for sanctions and diplomacy to take effect.

[21] On 10 April 2021, Iran began injecting uranium hexafluoride gas into advanced IR-6 and IR- 5 centrifuges at Natanz, but on the next day, an accident occurred in the electricity distribution network.

[36] Currently, the economy of Natanz is in the field of agriculture, people make a living by producing garden products such as pears, beets, walnuts, pomegranates and saffron.