Nathan Michael Sestina (born May 12, 1997) is an American professional basketball player for Valencia of the Spanish Liga ACB and the EuroCup.

As a senior at Cameron County High School, Sestina averaged 22.6 points and 14 rebounds per game and was named the North Tier Conference Player of the Year.

[3] Sestina suffered a season-ending shoulder injury four games into his freshman year and used a medical redshirt.

[9] In his first game with the Wildcats, Sestina scored seven points and grabbed a team-high six rebounds in a 69–62 win over top-ranked Michigan State and hit a key three-point shot in the second half.

In the next game versus Ohio State, Sestina scored a season-high 17 points in a 71–65 Kentucky loss.

[19] After going undrafted in the 2020 NBA draft, Sestina signed an Exhibit 10 contract for with the Brooklyn Nets on December 1, 2020.

[23] On July 8, 2021, he signed with Merkezefendi Belediyesi Denizli Basket of the Turkish Basketbol Süper Ligi (BSL).