His debut came on 29 January in the first stage of the Copa Libertadores away at Sporting Cristal, playing ten minutes in place of Marcelo Cirino in a 2–1 loss.

[8][9][10] Nine days after signing for Chelsea, it was announced that Nathan was join to Dutch side Vitesse Arnhem on loan, along with Isaiah Brown and Lewis Baker.

[11] He made his debut on 6 August in a UEFA Europa League third qualifying round second leg against Southampton at the GelreDome, replacing Baker for the final 21 minutes of a 2–0 home defeat for a 5–0 aggregate elimination.

[16] He played as Vitesse won the final of the KNVB Beker 2–0 against AZ Alkmaar on 30 April 2017 to lead the club, three-time runners up, to the title for the first time in its 125-year history.

[21] On 24 July 2018, Nathan agreed a deal to return to his native country to join Atlético Mineiro on a season-long loan, which was extended until mid-2020.

He made his debut with the under-17s during the 2013 FIFA U-17 World Cup, scoring five goals, including braces in the 6–1 group stage wins against Slovakia and hosts United Arab Emirates.