On October 5, 2015, he committed to William & Mary over offers from Temple, Duquesne, George Mason, and Canisius among others.

[2] Knight appreciated the rich history of the college and felt at home on the campus, saying it was an easy decision to make.

As a sophomore, he averaged 18.5 points, 7.3 rebounds and two blocks per game and was named second team All-Colonial Athletic Association (CAA).

Knight was named first team All-CAA as a junior after averaging 21 points, 8.6 rebounds, 3.5 assists and 2.3 blocks per game.

[4] Coming into his senior season, coach Shaver was fired and replaced by Dane Fischer while four players transferred, though Knight decided to stay on the team.

He did not appear for the Hawks' NBA G League affiliate, the College Park Skyhawks, as the team sat out the season due to the COVID pandemic.

For the 2021–22 season, Knight signed another two-way deal, this time with the Minnesota Timberwolves and their G League affiliate, the Iowa Wolves.

[12] In his first career NBA start on December 27, 2021, Knight recorded 20 points, 11 rebounds, one steal, and one block in a win against the Boston Celtics.