Nathaniel Charles Comfort is an American historian specializing in the history of biology.

He is an associate professor in the Institute of the History of Medicine at Johns Hopkins University.

He has written about the development of gene editing and its relationship to the United States' eugenics movement.

After working as a science writer at Cold Spring Harbor Laboratory,[7] he completed his Ph.D. in history at Stony Brook University in 1997.

[9] Comfort published 30 essays and reviews in Nature 2001–2019, and was one of the few authors selected to celebrate the magazine's 150th anniversary.