He attended public school until age fifteen, when he was apprenticed to the Boston printing firm of William and John Pendleton.

In late 1835, he issued a print illustrating a recent fire in New York City, Ruins of the Merchant's Exchange N.Y. after the Destructive Conflagration of Decbr 16 & 17, 1835 was published by the New York Sun, just four days after the fire, and was an early example of illustrated news.

In that year, The Sun published his print Awful Conflagration of the Steam Boat 'Lexington' in Long Island Sound on Monday Eveg Jany 13th 1840, by Which Melancholy Occurrence Over 100 Persons Perished, another documentation of a news event, three days after the disaster; the print sold thousands of copies.

Currier & Ives are best known as creators of popular art prints, such as Christmas scenes, landscapes, or depictions of Victorian urban sophistication; however, the firm also produced political cartoons and banners, significant historical scenes, and further illustrations of current events.

Currier died eight years after retiring, on November 20, 1888, at his home on Lion's Mouth Road in Amesbury, Massachusetts and is interred at Green-Wood Cemetery in Brooklyn.