[2] A railway line, built in a number of sections, once connected Horsham and Hamilton, running via Cavendish, Balmoral and East Natimuk until their closures in 1986 and 1988.

Natimuk has traditionally survived as a rural service centre for the surrounding grain and sheep farming community.

Natimuk's arts friendly focus has attracted and supported artists from nearby regions or urban areas to settle in the town.

Natimuk also fields three or four Australian Rules teams who compete in the Horsham & District Football League.

[8] Natimuk also hosts Goatfest, an annual climbing film festival, which coincides with the influx of climbers over the Easter holidays.