Women already in the hall of fame include Georgia O'Keeffe, Sacagawea, Annie Oakley, Dale Evans, Enid Justin, Temple Grandin and Sandra Day O’Connor.

The exterior is constructed with brick and cast stone with Terracotta finials formed in a ‘wild rose’ motif and glazed in vibrant colors.

A large painted mural by Richard Haas, bas-relief sculpture panels, and a series of hand-carved cast relief panels show scenes related to the Cowgirl's story and depict thematic messages such as ‘East Meets West’ and ‘Saddle Your Own Horse’ that represent the story told inside the Museum.

The Museum's interior is designed to provide a clear circulation path for visitors and creates central spaces for after-hours functions.

Two grand staircases providing overlooks into the rotunda are made of different metal finishes and colors with art deco inspired ornamental railings.

Permanent galleries include: The Rotating Exhibit Gallery has hosted past exhibits including: Donna Howell-Sickles: The Timeless Image of the Cowgirl; Georgia O'Keeffe and the Faraway: Nature and Image; Going to Texas: Five Centuries of Texas Maps; Paniolo: Cowboys and Cowgirls of the Hawaiian Frontier; Photographing Montana 1894-1928: The World of Evelyn Cameron; Ride: A Global Adventure; Texas Flags; The Cowgirl Who Became A Justice: Sandra Day O'Connor, Hard Twist: Western Ranch Women - Photographs by Barbara Van Cleve and No Glitz, No Glory.