[7] In 1998, Holles Street set up the Domino (Domiciliary Care In and Out of Hospital) and Home birth scheme through its team of community midwives.

[15][16] In April 2017, a former Master of the NMH, Dr Peter Boylan, resigned from the board over the influence of the Sisters on the new hospital.

[23] The Bishop of Elphin, Kevin Doran said that the Religious Sisters of Charity would have to obey the rules of the Roman Catholic church if they became owners of the National Maternity Hospital, and to follow teachings on "the value of human life and the dignity and the ultimate destiny of the human person".

"[24] In 2022, ownership of the order's shares in SVHG was transferred to a newly formed company, St Vincent's Holdings.

Aontú TD Peadar Tóibín stated that the family were shocked “by allegations that the medical professionals signing off on the abortions have a commercial interest in the companies that produced the fatally insufficient test”.

[28] The hospital, which is the national referral centre for complicated pregnancies, premature and sick infants, delivers over 7,000 babies per year.

[10] In June 2019, the Holles Street Hospital began work on an extension to the labour and delivery unit while awaiting relocation to the new facility which is not expected to be completed until 2024.