Llanquileo was born on 14 July 1984 in the Esteban Yevilao community of Puerto Choque, located in the commune of Tirúa in the Biobío Region.

[2][3] In 2011, Llanquileo condemned the sentencing of human rights attorney Karina Riquelme Viveros to 21 days in jail for allegedly providing legal advice to Mapuche activists prior to receiving a law degree.

[8] In 2018, Llanquileo was elected president of the Center for Research and Defense of the South (CIDSUR, Spanish: Centro de Investigación y Defensa del Sur).

[11] In 2021, Llanquileo launched her candidacy to serve on the Constitutional Convention of Chile to represent the Mapuche people, who have seven reserved seats on the body.

[15] This was considered a surprise given that Llanquileo had previously indicated her support for Loncón, and was the only Mapuche member of the Constitutional Convention to oppose her candidacy.

[17] In a 2018 interview, Llanquileo stated that the approaches towards Mapuche communities undertaken by Michelle Bachelet (Socialist) and Sebastián Piñera (conservative independent) were roughly as antagonistic.