[1][2] Naughty Bits is the story of Midge McCracken, aka Bitchy Bitch, an everyday woman angry at the world who frequently explodes with rage.

[3] The character made her first appearance in the Fantagraphics anthology Graphic Story Monthly #6 (June 1990).

Paul Constant of The Stranger called Naughty Bits "one of the best comic series I've ever read.

"Bye-Bye, Muffy," in Naughty Bits #28, was nominated for Best Short Story in the 2000 Eisner Awards.

[5] Life's a Bitch, an animated series spun-off from the X-Chromosome shorts, aired from 2003–2004 on Oxygen in the U.S. and on The Comedy Network in Canada.