Nawab Mohammad Ismail Khan is regarded as one of the founding fathers of the Islamic Republic of Pakistan due to the roles that he fulfilled for the cause of it.

He went on from there to attain his undergraduate credentials from St John's College, Cambridge to thereafter become a barrister of the Honourable Society of the Inner Temple (Inns of Court School of Law).

[1] In those days travel to the Great Britain was by ship from Bombay and around the Cape of Good Hope, consuming in excess of a month to reach.

Limited as the aim of the organisation was then, it included the advancement of the political rights and interests of the Muslims of India and prevention of the rise amongst themselves of any feeling of animosity towards other communities.

Nawab M. Ismail Khan actively associated himself with the All India Muslim League and became a member of its Working Committee in 1910 –- a position which he held for more than four decades.

[2][3][1] Nawab M. Ismail Khan would also contest and win the election to the Central Legislative Assembly, therefore having presided over the All India Khilafat Committee.

He was a member of the foundation committee of the Jamia Millia Islamia, but was opposed to the Indian National Congress's campaign for Swaraj through civil disobedience.

After the first World War –- in which India had aided the British with the men and material -– the people of the Subcontinent expected the initiation of an execution to meet their demands by means of home rule or a reasonable share in the Government.

[3][4][1] Nawab M. Ismail Khan was credited for his wisdom, sagacity, and above all his sincerity that had won him a place in the All-India Muslim League and its Working Committee.

It was a known fact that Nawab M. Ismail Khan was an independent opinionated leader who never hesitated to speak his mind even if it meant disagreeing with Mr. Jinnah.

Many such letters addressed to Mr. Jinnah as well as those written to Nawab M. Ismail Khan reveal his true position in the All-India Muslim League and the pivotal role that he played in the creation of Pakistan.

[5] It was the Nawab Sahib who with his band of colleagues, like Chaudhry Khaliquzzaman and Liaquat Ali Khan, kept the Muslim banner aloft in the United Provinces.

In 1937, the 25th Annual Conference of the All-India Muslim League was held in Lucknow under the chairmanship of Quaid-e-Azam (The Great Leader), Muhammad Ali Jinnah.

Prior to attending this historic session, Nawab Mohammad Ismail Khan suggested that the day held an auspicious meaning.

Over the active years of the All-India Muslim League, before eventually Pakistan was consummated, Nawab Sahib's cap would be lent to M. A. Jinnah on several occasions.

His association with the Aligarh University was deeply rooted due to his father, Nawab M. Ishak Khan, who had served the institution with passion and devotion as its trustee and secretary when it was the M.A.O.

His residence, the historical Mustafa Castle in Meerut, built in 1901 in memory of Nawab Shefta, was the headquarters of the Uttar Pradesh Muslim League and the center of bustling political activity for over four decades.