The Nebraska District includes approximately 249 congregations and missions, subdivided into 22 circuits, as well as 37 preschools, 39 elementary schools, 4 high schools, and 1 summer camp.

An earlier Nebraska District had existed from 1882 to 1922, before dividing until the 1970 reorganization.

District offices are located in Seward, Nebraska.

Delegates from each congregation meet in convention every three years to elect the district president, vice presidents, circuit counselors, a board of directors, and other officers.

[citation needed] Concordia University Nebraska, part of the LCMS Concordia University System, is located within the district.