Neelyville is a city in Butler County in Southeast Missouri, United States.

[4] Neelyville is included within the Poplar Bluff Micropolitan Statistical Area.

[7] Neelyville lies along U.S. Route 67 along with the future I-57 corridor According to the United States Census Bureau, the city has a total area of 1.15 square miles (2.98 km2), all land.

There were 213 housing units at an average density of 185.2 per square mile (71.5/km2).

28.2% of all households were made up of individuals, and 14.3% had someone living alone who was 65 years of age or older.

There were 215 housing units at an average density of 185.1 per square mile (71.5/km2).

30.9% of all households were made up of individuals, and 12.9% had someone living alone who was 65 years of age or older.