Neffs is an unincorporated community and census-designated place in northwestern Pultney Township, Belmont County, Ohio, United States.

[5] The local Neffs (or Neife) family came to Belmont County from Switzerland via Pennsylvania and Maryland.

[8] Neffs is located in eastern Belmont County in the northwest part of Pultney Township.

The center of the community lies in the valley of McMahon Creek, a tributary of the Ohio River.

Downtown Wheeling, West Virginia, is an additional five miles to the north from Bellaire.

The racial makeup of the community was 99.03% White, 0.35% African American, and 0.62% from two or more races.